Dear Colleagues,

Hydrogels is similar to tissue with soft, moist matrices and versatile physicochemical properties, showing vast applications in medical dressings, tissue sealants, drug carriers, and flexible electronics. And tissue adhesion is crucial; challenges include wet interface effects on adhesion, tissue elasticity, biocompatibility, and mimicking natural adhesion mechanisms like mussel. Bioinspired designs yield hydrogels with microneedles, suckers, and adhesive groups for biomedical, electronic, robotic, and environmental devices. Yet, commercializing smart adhesive

hydrogels faces hurdles like reversible adhesion, toxicity control, wet adhesion, tissue specificity, and mechanical enhancement.

We encourage the submission of original articles, reviews, case studies, short communications, critical comments, and perspective articles. We will accept manuscripts from different disciplines, addressing topics related to the scope.

This special issue will cover, but is not limited to, the following topics:

 Bioinspired Design and Fabrication

 Adhesive Mechanisms and Principles:

 Physicochemical Characterization

 Hydrogel Material Performance Optimization

 Biomedical Applications

 Expanded Applications in Innovative and Challenging Scenarios

Dr. Weijun Li

Dr. Yigang Shen

Guest Editors