Applied Chemical Engineering

Early diseases diagnosis in body fluids (serum and saliva) using infrared spectroscopy

Andrei A. Bunaciu

S.C. AAB_IR Research S.R.L.

Hassan Y. Aboul-Enein

Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Center

DOI: https://doi.org/10.24294/ace.v6i2.2097

Keywords: FT-IR analysis, biomedical analysis, human, serum, saliva, early disease diagnosis applications

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Abstract

Infrared spectroscopy it is becoming more and more useful in the field of biomedical research. Infrared spectroscopy has been used more and more to characterize biological matrixes, providing a simple way to obtain diagnostic and observational information from easily acquired samples. These tests are performed in order to monitor the changes, and in this way to characterize the biological matrix, with the aim of detecting the first signs that can diagnose a disease. Vibrational spectroscopy analysis of biological fluids has become more and more popular recently. Notably, the development of infrared spectroscopic screening of blood products, particularly blood serum and saliva, for illness diagnosis has attracted economic attention. This review examines some applications of the infrared spectroscopy method that was employed to examine human serum in order to detect disease at an early stage, published between 2017 and 2022.

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