Applied Chemical Engineering

Green fabrication of silver nanoparticles from Cinnamomum zeylanicum bark extract and evaluation of their antimicrobial efficacy

Mariya Banu Sri Rajasekaran

Centre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, 173, Agaram Road, Selaiyur, Chennai. Tamil Nadu, 600073, India.

Manoj Kumar Karuppan Perumal

Centre for Stem Cell-Mediated Advanced Research Therapeutics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, 600 077

Remya Rajan Renuka

Centre for Stem Cell-Mediated Advanced Research Therapeutics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, 600 077

Muruganandam Nagarajan

Department of Microbiology, ICMR-Regional Medical Research Centre, Port Blair, Andaman and Nicobar Islands, 744101, India

Angeline Julius

Centre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, 173, Agaram Road, Selaiyur, Chennai. Tamil Nadu, 600073, India.

Stalin Dhas Tharmathass

National Facility for Coastal and Marine Research (NFCMR) & Centre for Ocean Research (DST, FIST Sponsored Centre), MoES–Earth Science and Technology Cell, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu 600119, India

Antony Vincent Samrot

Department of Microbiology, Faculty of Medicine, Manipal University College Malaysia, Melaka, 75150, Malaysia.

DOI: https://doi.org/10.59429/ace.v8i3.5570

Keywords: Cinnamomum zeylanicum; AgNPs; green synthesis; antibacterial activity

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Abstract

In response to environmental concerns surrounding traditional silver nanoparticle synthesis, this study demonstrates an eco-conscious approach using Cinnamomum zeylanicum (C. zeylanicum) bark extract as a dual-function biological agent. UV‒visible spectroscopy confirmed the successful formation of the AgNPs. The characteristic surface plasmon resonance signal was observed. FTIR spectroscopy identified key functional groups involved in the process. These groups include amines, alkanes, alkenes, and alkyl halides. They play crucial roles in the reduction and stabilization of nanoparticles. TEM revealed quasispherical nanoparticles with a uniform distribution, ranging from 5 to 20 nm in diameter. XRD analysis confirmed their crystalline structure. Zeta potential measurements demonstrated good colloidal stability, and the nanoparticles exhibited significant antimicrobial efficacy, with substantial zones of inhibition in antimicrobial assays. This sustainable synthesis method eliminates the need for harsh chemicals and hazardous reaction conditions, providing a green pathway for producing antimicrobial silver nanoparticles. The approach offers promising applications in pharmaceutical products, medical devices, and water treatment systems while addressing environmental and toxicity concerns associated with traditional synthesis methods.

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