Applied Chemical Engineering

A review on benzimidazoles: Synthesis, properties, and therapeutic applications in medicinal chemistry

Hanan Ghadban Sha᾿aban

Chemistry Department, College of Science, Mustansiriyah University, Baghdad, 10052, Iraq

Firyal Wali Askar

Chemistry Department, College of Science, Mustansiriyah University, Baghdad, 10052, Iraq

DOI: https://doi.org/10.59429/ace.v8i2.5647

Keywords: benzimidazole; heterocyclic compounds; biological activity; antiviral agents; microwave-assisted synthesis; green chemistry

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Abstract

Heterocyclic compounds, characterized by rings containing non-carbon atoms like nitrogen, oxygen, or sulfur, are fundamental in diverse fields. This review provides an overview of heterocyclic chemistry, with a focused examination of benzimidazoles. It covers their structure, chemical properties, synthetic methods (including classical and modern techniques emphasizing efficiency and sustainability), and broad therapeutic applications across various disease areas, highlighting their significance in drug development and materials science. From (2018-2024)

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